MHC I antigen processing

Machine Learning for MHC I peptide classification

A toy model that attempts to classify peptides from my some of my experiments according to one of five MHC class I allotypes present in the cells I use.

MHC dynamics dashboard

A dashboard to display the results of the MHC I HDX project

Selector function of MHC I molecules is determined by protein plasticity

This project sought to explain the mechanism of peptide selection by two functionally distinct MHC I allotypes using a combination of molecular dynamics and mathematical modelling of biochemical experiments.